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인위적인 기아상태의 반복 노출, 지속은 몸을 위급상황에 대비한 체지방 축적 모드로 적응 시킨다.단기적인 효과는 확실히 있다. 그러나 장기적인 관점에서의 그 예상되는 부작용이 매우 크다.Short-term food restriction followed by controlled refeeding promotes gorging behavior, enhances fat deposition, and diminishes insulin sensitivity in miceKara L. Kliewer,a Jia-Yu Ke,a Michael B. Stout,a Rachel Cole,a Varman T. Samuel,b Gerald I. Shulman,b,c,d and Martha A. Belurya,*Author information ► Copyright and License information ► DisclaimerCould intermittent fasting diets increase diabetes risk?Fasting every other day to lose weight impairs the action of sugar-regulating hormone, insulin, which may increase diabetes riskDate:May 20, 2018 Source:European Society of Endocrinology Summary:Fasting every other day to lose weight impairs the action of sugar-regulating hormone, insulin, which may increase diabetes risk. These findings suggest that fasting-based diets may be associated with long-term health risks and careful consideration should be made before starting such weight loss programs. • 실험에서의 단식은 4시간 동안의 음식 섭취. 20시간의 금식를 기준.